TIRZEPATIDE
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Mounjaro is a brand-name version of the generic medication Tirzepatide, which mimics the effect of the natural gut hormones GLP-1 and GIP. Mounjaro is only available via a prescription and is licensed for the treatment of weight loss and weight maintenance when used alongside a reduced-calorie diet and increased physical activity. It works by targeting receptors in the digestive tract and brain to regulate appetite and blood sugars and slow down digestion, creating a feeling of fullness for longer.
You should not use this drug if:
You are pregnant or breastfeeding
You are trying to conceive
You have a personal or family history of medullary thyroid carcinoma (MTC)
You have a personal or family history of Multiple Endocrine Neoplasia Syndrome type 2 (MEN2)
You are taking certain medications
Tirzepatide is a brand-name version of the generic medication Tirzepatide, which is a type of medication that targets GLP-1 receptors and GIP receptors. It works in a similar way to other GLP-1 medications, with the added benefit of also targeting the GIP receptor.
The group of GLP-1 analogues (GLP-1a) mimics the effect of the natural gut hormone GLP-1, helping to balance blood sugar levels and suppress appetite. By slowing down gastric emptying, the medication can lead to an increased feeling of fullness and reduced appetite.
Abdomen (5cm away from your belly button)
Thighs
Upper arms - if administering in the arm, we recommend asking another person to give you the injection in the back of your upper arm
We advise you to mix up your injection sites to minimise discomfort.
You self-inject Mounjaro at home once a week (on the same day each week), under your skin, in the subcutaneous fat—don’t worry, the needle is very small, and most patients describe it as a pin-prick feeling. When you inject Mounjaro, you should always follow the instructions accurately and be in a safe and clean environment.
Prepare for the injection
Wash your hands with soap and water before preparing your pen.
Check the solution inside the pen is colourless to slightly yellow.
Attach the needle and remove both needle caps safely.
Only use this medication if the solution is colourless to slightly yellow. If the solution is cloudy or you can see various particles, discard it and speak to your doctor. Never reuse or share needles with others.
Check the flow
Dial your Mounjaro pen to the third line.
You will need to complete this step each time you use a new Mounjaro pen. Hold your pen horizontally with the needle pointing downwards.
Press the dose button until the pointer is lined up with “0 mg”.
At this point, you should notice a drop of solution will appear at the tip of your needle.
Select your dose
Dial your pen to the dose you have been prescribed - turn the dial until it stops and the number 1 is shown in the dose window.
Do not inject more than your prescribed dose. Always follow your healthcare professional’s instructions.
Inject your dose
Insert the needle into your abdomen, upper arm or thigh.
Press and hold the dose button to administer the solution until the pointer is aligned with “0 mg.”
Keep holding the dose button for an additional 5 seconds to ensure the dose is fully administered.
Gently remove the injection.
Do not release the dose button until the needle has been removed from your skin.
Only inject into the areas mentioned in the patient information leaflet (abdomen, thigh and upper arm). Make sure to rotate the injection site with each dose to avoid discomfort.
Discard your needle
Carefully attach the outer needle shield back on the needle and remove your needle from the pen.
Dispose of the needle in the yellow sharps bin provided.
Do not throw your used needles away in your household rubbish bin. Keep them out of reach of children and pets.
Store your Mounjaro pen
After every use, be sure to place the pen’s cap back on. This protects the medication from light.
You should store your pen without needles attached.
Store Mounjaro for up to 30 days at room temperature (so long as this is not above 30˚C) or in a refrigerator cooling element (2˚C to 8˚C.)
Keep your Mounjaro pen on hand and with you at all times.
Do not leave your pen places where it could get too hot or too cold as this may cause the solution to become cloudy and unusable. Do not freeze this medication or store it in direct sunlight. Do not store this medication in your car glove compartment.
Ensure this medication is stored somewhere others cannot reach it, particularly children and pets.
SEMAGLUTIDE
Wegovy is a licensed weight-loss medication approved by the UK’s Medicines and Health products Regulation Agency (MHRA). It’s a brand-name version of the generic medication Semaglutide, which mimics the effect of the natural gut hormone GLP-1. The medication works by regulating digestion and suppressing appetite so you’ll want to consume less food. You can be prescribed Wegovy for weight loss if you have a BMI over or equal to 30, or over or equal to 27 with certain weight-related conditions. The medication should always be used as part of a programme that includes a healthy diet and exercise. As a member of Curate, your coach will help you navigate what to eat, how to incorporate exercise into your lifestyle, and how to change your mindset to reach your weight loss goal.
You should not use this drug if:
You are pregnant or breastfeeding
You are trying to conceive
You have cancer
You have a personal or family history of medullary thyroid cancer
You have a personal or family history of Multiple Endocrine Neoplasia Syndrome type 2 (MEN2)
You suffer from liver, kidney or congestive heart failure
You suffer from pancreatitis (inflammation of the pancreas)
You suffer from type 1 diabetes or diabetic retinopathy
You have a history of an eating disorder (eg. anorexia, bulimia)
You have a history of gallbladder problems
You have a history of Inflammatory bowel disease or gastroparesis
Wegovy is a brand-name version of the generic medication Semaglutide, which is a type of medication called a glucagon-like peptide 1 receptor agonist. To keep things simple, we call these medications “GLP-1s'' for short. The group of GLP-1 analogues (GLP-1a) mimics the effect of the natural gut hormone GLP-1, helping to balance blood sugar levels and suppress appetite, resulting in reduced body weight.
In a nutshell, Wegovy helps to support weight loss by:
Reducing appetite - so you are less hungry
Reducing cravings - so it’s easier to make healthy choices
Reducing your ‘set point’ - so you can lose more weight before starting to plateau
Weight-loss medication has been used for many years, but the latest generations of medication have fewer side effects and increased effectiveness. It’s important to note that the medicine does not provide sustained weight loss alone. To get the most out of a course of Wegovy, you must consider it as a tool to use in combination with healthy lifestyle changes for long-term weight management.
You self-inject Wegovy at home once a week (on the same day each week), under your skin, in the subcutaneous fat—don’t worry, the needle is very small, and most patients describe it as a pin-prick feeling. When you inject Wegovy, you should always follow the instructions accurately and be in a safe and clean environment.
Prepare for the injection
Wash your hands with soap and water before preparing your pen.
Check the solution inside the pen is colourless to slightly yellow.
Attach the needle and remove both needle caps safely.
Only use this medication if the solution is colourless to slightly yellow. If the solution is cloudy or you can see various particles, discard it and speak to your doctor. Never reuse or share needles with others.
Check the flow
Dial your Wegovy pen to the third line.
You will need to complete this step each time you use a new Wegovy pen. Hold your pen horizontally with the needle pointing downwards.
Press the dose button until the pointer is lined back up with “0 mg”.
At this point, you should notice a drop of solution will appear at the tip of your needle.
Select your dose
Dial your pen to the dose you have been prescribed - turn the dial until it stops and the relevant dose is shown in the dose window.
Do not inject more than your prescribed dose. Always follow your healthcare professional’s instructions.
Inject your dose
Insert the needle into your abdomen, upper arm or thigh.
Press and hold the dose button to administer the solution until the pointer is aligned with “0 mg.”
Keep holding the dose button for an additional 5 seconds to ensure the dose is fully administered.
Gently remove the injection.
Do not release the dose button until the needle has been removed from your skin.
Only inject into the areas mentioned in the patient information leaflet (abdomen, thigh and upper arm). Make sure to rotate the injection site with each dose to avoid discomfort.
Discard your needle
Carefully attach the outer needle shield back on the needle and remove your needle from the pen.
Dispose of the needle in the yellow sharps bin provided.
Do not throw your used needles away in your household rubbish bin. Keep them out of reach of children and pets.
Store your Wegovy pen
After every use, be sure to place the pen’s cap back on. This protects the medication from light.
You should store your pen without needles attached.
Store Wegovy for up to 30 days at room temperature (so long as this is not above 30˚C) or in a refrigerator cooling element (2˚C to 8˚C.)
Keep your Wegovy pen on hand and with you at all times.
Do not leave your pen places where it could get too hot or too cold as this may cause the solution to become cloudy and unusable. Do not freeze this medication or store it in direct sunlight. Do not store this medication in your car glove compartment.
Ensure this medication is stored somewhere others cannot reach it, particularly children and pets.
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